Police say at least one person has died after a driverless train carrying light crude oil exploded in the Canadian town of Lac-Megantic.
The blast sent a fireball and black smoke into the air, forcing the evacuation of 1,000 people.
Dozens of buildings were destroyed in the town, about 250 km (155 miles) east of Montreal.
The train's 73 cars reportedly uncoupled from a parked engine and derailed early on Saturday.
Local media reported 60 people missing, although police officials have not confirmed this.
The cause of the derailment was not immediately clear.
Some 120 fire fighters have been fighting the blaze, which continued more than 12 hours after the blast.
They have been unable to approach the centre of the devastation.
Eyewitnesses reported that the town centre was crowded at the time of the blast, and that "chaos" ensued.
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